some questions about clinvar database

Question

[cginsea]

Dear All I am a user of clinvar database. (ftp://ftp.ncbi.nlm.nih.gov/pub/clinvar/vcf_GRCh37/clinvar_20181028.vcf.gz) which downloaded from ftp site, while I noted that these variations with high review status level can be searched in clinvar website with have high review status level. Some examples were listed as follows: 37861, 229653, et al. So, my question is which source can be used in my research and why these variations with high review status were being deleted in vcf file. Thanks for your help. Best Regards

[finswimmer]

Interesting, I have an older release of clinvar here (2017-10-29) and there these IDs are included, but not in the current release.

I would suggest you try to contact someone at clinvar and ask for clarification. Please report the answer here.

fin swimmer

[cginsea]

Thanks, I have contacted clinvar through E-mail and twitter message, while I didn't receive any responses, can you provide any useful information about clinvar contacting?

[Kevin Blighe]

Go HERE and click on the Write to the Help Desk link, conveniently in small font and hidden away on the bottom-right. If you want a quicker response, I would suggest using a University / Academic email.

[cginsea]

Thanks, I would paste any responses if I received.