Question: How to find conserved domains
gravatar for Gina
3 months ago by
Gina0 wrote:


How can I find conserved domains in a protein sequece, and why are some sequences conserved and some not? Which useful tools can you recommend to find conserved domains?

conserved domains • 253 views
ADD COMMENTlink modified 4 weeks ago by Biostar ♦♦ 20 • written 3 months ago by Gina0

This sounds like a homework/assignment question. If that's the case, it will be closed as off-topic unless you first show us your efforts to tackle the questions. We will be happy to steer you in the right direction after that.

ADD REPLYlink written 3 months ago by jrj.healey10k

Your question is too general. What organism you are interested in?

Prokaryotic or eykaryotic one?

There are a lot of posts in Biostars about protein domains.

Just go to the left-hand upper corner, click

'LATEST' and type your question (conserved domains in a protein sequence)

to an empty string in the middle of the page. But add some details. I've found several links,

but I am not sure this will help you a lot - they are also general.

Also look at the right panel - there may be very recent threads as well.

Uniprot – is a good sourse:

Conserved Domain Batch Retrieval

pfam and hmm databse of PFAM

protein domain software

PROSITE and ConPlex

A: Tool For Evolutionary Conservation Of Protein Folds

Domain prediction

How can find conserved domains of protein's sequence offline?

domains from multiple sequences

Extract Domain Sequences From Multiple Sequences

Protein domain visualization tools

Looking for a protein domain visualisation tool

ADD REPLYlink modified 4 weeks ago • written 4 weeks ago by natasha.sernova3.3k
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