How to get AF in TCGA MutSigNozzleReport2CV Level_4
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5.4 years ago
H.Hasani ▴ 990

Dear all,

after downloading TCGA-SNP level 4 from firehose; I noticed that the files have either all or some of the columns bellow. I'm wondering if they are indeed Allele Frequencies that were obtained from phase1 & 3 of 1000G project (as the name might reveal)? if that is the case then what are dbNSFP_ESP refer to? Moreover, how can I obtain TCGA-AF and not the reported AF?

Thank you in advance

i_1000gp3_AF 
i_1000gp3_AFR_AF
i_1000gp3_AMR_AF       
i_1000gp3_EAS_AF
i_1000gp3_EUR_AF
i_1000gp3_SAS_AF       
i_dbNSFP_1000Gp1_AF
i_dbNSFP_1000Gp1_AFR_AF
i_dbNSFP_1000Gp1_AMR_AF
i_dbNSFP_1000Gp1_ASN_AF 
i_dbNSFP_1000Gp1_EUR_AF 
i_dbNSFP_ESP6500_AA_AF 
i_dbNSFP_ESP6500_EA_AF
SNP tcga alele fraction • 698 views
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