Question: Identifying pri-microRNA sequence from microRNA sequence
gravatar for anand.gururajan
23 months ago by
anand.gururajan0 wrote:

Hi all.

Given miRNA-seq data, is there a way to bioinformatically predict the sequence of the pri-miRNAs?

Does anyone reference to a paper with an algorithm (in R or python) for doing this?

And lastly, has anyone experimentally validated that a specific pri-miRNA produces a specific miRNA?

Thanks all.


microrna rna-seq • 546 views
ADD COMMENTlink modified 9 months ago by Biostar ♦♦ 20 • written 23 months ago by anand.gururajan0

To predict pri-miRNA sequence, sequencing data (RNA-seq, histone chip-seq, CAGE-seq and other data) is necessary, and very difficult to predict simply based on DNA sequence. Here is one paper Of course there are other papers which have implemented similar idea to predict pri-miRNA.

ADD REPLYlink written 23 months ago by Chirag Nepal2.2k
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