Question: Identifying pri-microRNA sequence from microRNA sequence
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gravatar for anand.gururajan
23 months ago by
anand.gururajan0 wrote:

Hi all.

Given miRNA-seq data, is there a way to bioinformatically predict the sequence of the pri-miRNAs?

Does anyone reference to a paper with an algorithm (in R or python) for doing this?

And lastly, has anyone experimentally validated that a specific pri-miRNA produces a specific miRNA?

Thanks all.

Anand

microrna rna-seq • 546 views
ADD COMMENTlink modified 9 months ago by Biostar ♦♦ 20 • written 23 months ago by anand.gururajan0

To predict pri-miRNA sequence, sequencing data (RNA-seq, histone chip-seq, CAGE-seq and other data) is necessary, and very difficult to predict simply based on DNA sequence. Here is one paper https://www.ncbi.nlm.nih.gov/pubmed/26673698 Of course there are other papers which have implemented similar idea to predict pri-miRNA.

ADD REPLYlink written 23 months ago by Chirag Nepal2.2k
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