how to compere Gene ontology for some data set from micorraray with differentiallay expressed genes

Question

[Calangoa]

Hi there, I have a question, how to compere Gene ontology for some data set from micorraray with differentiallay expressed genes? I know there are different option for annotation individual sets like BinGO, DAVID and etc but I want to compare GO for a set of DEGs. Is Hierarchical clustering a good chose?

Any suggestion would be helpful

Thanks in advance

Answer 1

[jared.andrews07]

For something like this, GO enrichment is really what you want. There are lots of tools that can do that, including several R packages like enrichR and clusterProfiler, which is a personal fave for the figures it can generate.

[Calangoa]

Thanks Jared for your helpful answer