Could you possibly help me understand in simple terms what is a "probe" (ex: cg06928838 (GSTP1 gene)) in an Infinium HumanMethylation450K BeadChip and how is a probe "made"? I mean to get methylation values.
Am I correct in saying that probes target specific loci of genes, not the whole gene to get a methylation value?
I would appreciate all responses. Thanks!