Entering edit mode
5.4 years ago
whtopjazz
•
0
I'm new to imputation. And I filtered samples and markers before imputation. But I do not know, if I should filter SNPs by LD before imputation.
For example, use plink --indep-pairwise 50 1 0.75
to remove SNPs in high LD.
Can anyone explain why should I do that or not?
Thanks
There are tutorials/manuals online for imputation, pick one and follow through. (I wouldn't prune anything)