Question: Align sequences against reference MSA
gravatar for kristjan
3 months ago by
kristjan130 wrote:

What program can align a group of unaligned sequences against a large multiple sequence alignment? I need my sequences to have the same alignment length as the reference alignment, but they cannot be combined (like MAFFT -add does).

msa alignment • 180 views
ADD COMMENTlink modified 3 months ago by Biostar ♦♦ 20 • written 3 months ago by kristjan130

Do you mean align one or more sequences to a consensus sequence generated using MSA?

ADD REPLYlink written 3 months ago by Sej Modha4.1k

I believe CLUSTAL's profile alignment mode can do this (you align new sequences against the existing alignment)

ADD REPLYlink written 3 months ago by jrj.healey11k
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