I know this is not a pure bioinformatics question but my lab has been researching methods of obtaining large amounts of image sets automatically in order to extract useful histological features out of them and correlate with sequencing data. You may find similar work there
https://arxiv.org/abs/1703.02442 https://www.nature.com/articles/nature21056 https://www.nature.com/articles/s41591-018-0177-5
Our main material is H&E stained slides obtained through multi layered TMA dissection from FFPE tumors. Problem is that we want to take many optical microscopy photos in different zoom levels with optimized brightness and focus. Do you know if that kind of technology is generally commercially available?