RNA Expression Pathway Database
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5.4 years ago
DVA ▴ 630

Could you please recommend me a database where I can get gene expression pathway data? Essentially, this database should have information along the lines of "expression of X causes an increase/decrease in the expression of Y".

I am studying RNA-seq data and information about "protein X binds protein Y" or "protein X degrades protein Y" is NOT really useful to me right now, unless that is somehow translated into an expression change. I know there are a lot of pathway databases out there and one of them might cover this, but I am fairly new to this subject and would appreciate some guidance. Thank you very much in advance.

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I am afraid that what you want: "expression of X causes an increase/decrease in the expression of Y" is too simplistic for real biology. What I mean is that biology is more complex than finding one to one gene expression relationships.

Databases containing data with "protein X binds protein Y" or "protein X degrades protein Y" are empirically tested in experiments. When you want to know if expression of X causes increase in the expression of Y, you have too many other factors that may cause this increase.

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