Question: RNA Expression Pathway Database
0
gravatar for DVA
5 weeks ago by
DVA480
United States
DVA480 wrote:

Could you please recommend me a database where I can get gene expression pathway data? Essentially, this database should have information along the lines of "expression of X causes an increase/decrease in the expression of Y".

I am studying RNA-seq data and information about "protein X binds protein Y" or "protein X degrades protein Y" is NOT really useful to me right now, unless that is somehow translated into an expression change. I know there are a lot of pathway databases out there and one of them might cover this, but I am fairly new to this subject and would appreciate some guidance. Thank you very much in advance.

database • 138 views
ADD COMMENTlink modified 29 days ago by Biostar ♦♦ 20 • written 5 weeks ago by DVA480

I am afraid that what you want: "expression of X causes an increase/decrease in the expression of Y" is too simplistic for real biology. What I mean is that biology is more complex than finding one to one gene expression relationships.

Databases containing data with "protein X binds protein Y" or "protein X degrades protein Y" are empirically tested in experiments. When you want to know if expression of X causes increase in the expression of Y, you have too many other factors that may cause this increase.

ADD REPLYlink written 5 weeks ago by b.nota5.7k
Please log in to add an answer.

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 793 users visited in the last hour