Question: How to interpret the eQTLs in cancer
gravatar for magicpants
3 months ago by
magicpants60 wrote:

According to the paper PancanQTL: systematic identification of cis-eQTLs and trans-eQTLs in 33 cancer types, they conducted the eQTL mapping using RNA-seq and genotype data from TCGA.

I am a bit confused about the meaning of cancer eQTL. I know that an eQTL is a locus that explains a fraction of the genetic variance of a gene expression phenotype, so the eQTLs identified from cancer (and normal?) samples are the loci that may lead to gene expression disturbance during tumor transformation and development?

eqtl snp rna-seq tcga • 168 views
ADD COMMENTlink modified 3 months ago • written 3 months ago by magicpants60
Please log in to add an answer.


Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1902 users visited in the last hour