Question: How to interpret the eQTLs in cancer
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gravatar for magicpants
3 months ago by
magicpants60
magicpants60 wrote:

According to the paper PancanQTL: systematic identification of cis-eQTLs and trans-eQTLs in 33 cancer types, they conducted the eQTL mapping using RNA-seq and genotype data from TCGA.

I am a bit confused about the meaning of cancer eQTL. I know that an eQTL is a locus that explains a fraction of the genetic variance of a gene expression phenotype, so the eQTLs identified from cancer (and normal?) samples are the loci that may lead to gene expression disturbance during tumor transformation and development?

eqtl snp rna-seq tcga • 168 views
ADD COMMENTlink modified 3 months ago • written 3 months ago by magicpants60
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