how to change indel to smallest length in vcf
0
0
Entering edit mode
5.3 years ago
kumajis • 0

I want to annotate VCF with HGMD database information by sql, but there is some problem with indel records, such as :

In VCF the variant is 5 13868103 . TA T, but in HGMD, it becomes 5 13868104 A .

So for annotation correct, should I change variants like 5 13868103 . TA T to 5 13868104 . A . in VCF (if so, what tools could do this), or there are some other ways to solve it.

Thanks.

next-gen annotation indel VCF • 931 views
ADD COMMENT
0
Entering edit mode

Hello 1097049297 ,

if possible you should try to make a vcf out of the sql database and normalize the result with bcftools norm.

fin swimmer

ADD REPLY

Login before adding your answer.

Traffic: 3156 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6