Question: How to create BigWig files with normalised signal using ChIP-seq and Input?
1
gravatar for biostart
2.2 years ago by
biostart350
Germany
biostart350 wrote:

Hello,

I have ChIP-seq and Input, and want to display occupancy normalised by the Input (e.g. input-subtracted, or divided by the Input). is there some solution to create one BigWig file starting from two BAM files with the ChIP-seq and the Input?

Thanks!

bigwig chip-seq • 1.4k views
ADD COMMENTlink modified 2.2 years ago by Devon Ryan98k • written 2.2 years ago by biostart350
2
gravatar for Devon Ryan
2.2 years ago by
Devon Ryan98k
Freiburg, Germany
Devon Ryan98k wrote:

You're looking for bamCompare from deepTools, which can create both input-subtracted and signal divided by input tracks.

ADD COMMENTlink written 2.2 years ago by Devon Ryan98k
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