I have a set of genes associated with a particular complex disease. All the genes are in the HGNC gene symbol format. My aim is to construct a protein interaction directed network in which physical binary interactions are bidirectional and genetic/ functional interactions are unidirectional. Could someone can suggest a database where I can find physical interactions among the given set of genes?. One which I found is HuRI interactome http://interactome.baderlab.org, which doesn't give output for a large set of input genes (there are about 1200 genes in the input gene set). Also, where do I get functional interaction data among these genes? Is the STRING database a good option?