Question: Why is the pacbio bam 10X the original bam file size?
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gravatar for peri.tobias
11 months ago by
peri.tobias10
peri.tobias10 wrote:

Running the genomicconsensus arrow on aligned raw reads against a de novo pacbio assembly (1 Gbase assembly).

Used minimap2 for the aligned.bam and then pbbamify to format for use with arrow.

Can't find information on what this reformatting does but the initial aligned.bam = 35G and the pb_aligned.bam = 350G. Does this match the experience of others?

thanks, Peri

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