Question: Estimating SNP heritability for related individuals from a SNP array
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gravatar for drr719
29 days ago by
drr7190
drr7190 wrote:

Hi, I am analysing some SNP data and need to calculate heritability (h2) for the SNPs I identify. This is complicated a little by the fact that this study is based on trio/quad data of case, mother, father and optional sibling. Is anyone aware of the "go to" tools for this? Are there confounding factors I need to take into account? Thanks in advance for any assistance.

ADD COMMENTlink modified 29 days ago by Sam2.2k • written 29 days ago by drr7190
0
gravatar for Sam
29 days ago by
Sam2.2k
London
Sam2.2k wrote:

You can try using GCTA GREML-KIN which can take into account of relateship information when calculating the SNP heritability

ADD COMMENTlink written 29 days ago by Sam2.2k
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