Question: Estimating SNP heritability for related individuals from a SNP array
gravatar for drr719
29 days ago by
drr7190 wrote:

Hi, I am analysing some SNP data and need to calculate heritability (h2) for the SNPs I identify. This is complicated a little by the fact that this study is based on trio/quad data of case, mother, father and optional sibling. Is anyone aware of the "go to" tools for this? Are there confounding factors I need to take into account? Thanks in advance for any assistance.

ADD COMMENTlink modified 29 days ago by Sam2.2k • written 29 days ago by drr7190
gravatar for Sam
29 days ago by
Sam2.2k wrote:

You can try using GCTA GREML-KIN which can take into account of relateship information when calculating the SNP heritability

ADD COMMENTlink written 29 days ago by Sam2.2k
Please log in to add an answer.


Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1589 users visited in the last hour