I am observing focal and broad events in CNVs found in the TCGA. I’ve noticed the post segmented CNV data has number of probes as low as 2, and produce segments that appear as possible noise (especially in normal profiles). I am curious if there is a minimum number of probes threshold, preferably with a reference, to filter out low number of probe segments? I know the “join segment” option on GISTIC2.0 has a default of 4, but I can’t find a reference or justification for this choice of minimum number of probes. Any advice or assistance is welcome, and thank you!
Question: Number of Probes per Segment for TCGA CNVs
6 weeks ago by
jrlarsen • 0
jrlarsen • 0 wrote:
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