Question: Low Complexity in Proteins
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gravatar for BiomedicalTissueIng
6 months ago by
BiomedicalTissueIng0 wrote:

Hi everyone! I'm investigating about Low Complexity sequences in proteins but I have some problems chosing a Threshold that could actually helps to sunder when the LC content could influence the protein's behavior,e.g when i get a protein with five LC residues I would be prone to put that one in ~LC cluster. So the real question is, when do I have a content such to consider the LC presence significant in my sequence of AA?

Thank you in advance

gene • 237 views
ADD COMMENTlink modified 6 months ago • written 6 months ago by BiomedicalTissueIng0
1

See these posts, they may help you:

They show how to deal with LCR : some soft determines if the regions are LC-ones or not,

some mask them, etc.

Analysis Of Low-Complexity Regions

A: Masking Algorithms In Literature

A: Given Sequences, How To Compute A Low Complexity Score For Each Sequence?

How To Mask Low-Complexity Regions In Proteins?

Looking For Tools To Identify Low Complexity Regions In A Protein (Similar To Seg That Seems Unavailable)

A: Is There Any Script To Count Repeats In Protein Sequences?

Given Sequences, How To Compute A Low Complexity Score For Each Sequence? - this is almost answer to your question.

Complex Genomic Regions - see algorithms at the bottom of the post.

masking low complexity regions in a protein database for BLAST - masking - is it a good idea or not?

ADD REPLYlink modified 6 months ago • written 6 months ago by natasha.sernova3.5k

I'll check it out!Thanks!

ADD REPLYlink written 6 months ago by BiomedicalTissueIng0
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