Question: How to merging multiple GSEs with different GPLs?
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gravatar for maryam.sabet
5 months ago by
maryam.sabet0 wrote:

I want to merging multiple GSEs with different GPLs(with R) ,but I don't know which package is suitable for merging, for this purpose, VirtualArray and InSilicoMerging packages do not efficient.

R • 189 views
ADD COMMENTlink written 5 months ago by maryam.sabet0

Could you explain what are you trying to do? GPLs describe different GEO platform (Sequencing, array or even RT-PCR) and unless they are measuring similar things, you can not merge them. On the top of that, you need to care about different normalization and overall normalization of merged samples.

ADD REPLYlink written 5 months ago by Santosh Anand4.9k

I want to find similar genes between different GPL then compare expression level of these genes to find out which have significant difference.

ADD REPLYlink written 5 months ago by maryam.sabet0
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