Does it make sense to use methylation data for GESA
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5.4 years ago
CY ▴ 750

I came across ChAMP which analyzes methylation data using GSEA. I know that DNA methylation and corresponding mRNA expression are interconnected in some degree. However, does it really make sense to use gene groups clustered by methylation for GSEA which is based on mRNA expression?

GESA methylation expression • 1.2k views
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