Entering edit mode
5.1 years ago
swkim
▴
20
Hi,
I am introducing our recent software RePlow that detects low-frequent (VAF<1%) somatic mutations using technical replication for NGS sequencing.
https://www.nature.com/articles/s41467-019-09026-y
I think our paper explains why calling mutations with <1% VAF is generally difficult, and what is the best way to resolve the problems. Hope you enjoy this!