Question: How does RNA relative abundance relate to SNPs and eQTLs?
gravatar for rattus8
13 months ago by
rattus840 wrote:

I am looking at the GTex portal for significantly different expression of certain genes, within individual tissue types. Is this the same thing as saying that the gene has a significant normalized effect size associated with an eQTL in a tissue? (For instance:

I'm having trouble figuring out how the eQTL plays in, vs. SNP vs. plain old normalized transcript counts. I'm not sure why SNPs and variants come into play. Thank you!!

eqtl abundance gtex rna snp • 368 views
ADD COMMENTlink modified 13 months ago by geek_y10k • written 13 months ago by rattus840
gravatar for geek_y
13 months ago by
geek_y10k wrote:

Differential gene expression is very different from an eQTLS gene (eGene) between tissues . They are completely different concepts. I would suggest to spend time in understanding an eQTL/eGene vs differential gene by reading literature.

PS: SNPs and variants (SNVs) are not very different.

ADD COMMENTlink written 13 months ago by geek_y10k
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