How to generate a mutated DNA sequence?
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2.5 years ago

Hi, I'm a newbie in bioinformatics, I just want to know how to build an accurate (not random) mutated sequence of a given gene. With the mutations coming from .mafs provided by TCGA.(Just taking into account point mutations). Thanks in advance

I've been reading a lot but the more I read the less I know, so all help is welcome thanks I advance

sequence mutations • 719 views
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Give mutate.sh from BBMap suite a try. Run the command without any options to look at the in-line help.