Entering edit mode
5.5 years ago
lefthandgergo
▴
10
Hi! I'd like to compare expression levels of given genes between two subgroups of the TCGA cohort. I have expression data, derived from the PanCancer Atlas, from cbioportal in two different files: "data_RNA_Seq_v2_expression_median.txt" (RSEM) and "data_RNA_Seq_v2_mRNA_median_Zscores.txt". Which could I use for comparing expression levels between sample groups? Or both of them can be used for this purpose?
Thanks!
Hi, by "comparing expression levels between sample groups" you mean differential expression analysis?
Actually what I plan is to collect all expression values for each group, and then look for significant differences between them using Wilcoxon test.