Question: Need help regarding hypothesis of branch model
0
gravatar for rprog008
14 months ago by
rprog00870
rprog00870 wrote:

enter image description hereRespected member, I am new learner of codeml and designing my experiment for analysis of 14 mammalian coding sequence based on the tutorial at https://link.springer.com/protocol/10.1007%2F978-1-4939-1438-8_4.

In my analysis, human is “foreground branch”.

I am getting confused with the hypothesis of branch model. image of the Hypothesis given in the link below

https://ibb.co/k49D9F4

My question is in first comparison (Free-ratio vs. one-ratio model), we are already testing if for a tree of s species, is ω different among lineages?

Then why are we doing Two-ratio vs. one-ratio model to test "Are the foreground branches that you specify more likely to have different ω from background branches?"

I think in both the case we are getting same result.

Please help

codeml branch-site models • 232 views
ADD COMMENTlink modified 14 months ago • written 14 months ago by rprog00870
Please log in to add an answer.

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1724 users visited in the last hour