How to convert DS value for chrX non-PAR SNPs in male
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2.7 years ago
Apprentice ▴ 90

Hi.

I have imputed male data of SNPs located on chrX non-PAR (pseudo autosomal region) using 1000 genomes phase 3 as a refrence. The imputation was performed by using minimac3.

The imputed genotypes have GT, DS, and GP information. The DS data is ranging from 0 to 1.

In many X-wide association studies, the imputed male genotype is coded ranging from 0 to 2. For example, https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1004127

Could you tell me how to convert the DS data ranging 0 to 1 into the data ranging 0 to 2?

SNP imputation snp chrX PAR • 793 views
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