Question: Infer pedigree from Kinship coefficients
0
gravatar for landscape95
5 months ago by
landscape95160
landscape95160 wrote:

Hi everyone, I have a kinship file computed by KING software which contains 5 columns: ID1, ID2, HetHet, IBS0, Kinship. I also have a fam file but missing the father and mother data for each individuals. Now is there any way to recover the pedigree data from the current data I have? Your help is really appreciated!

kinship gwas • 212 views
ADD COMMENTlink modified 4 months ago by margherita.col20 • written 5 months ago by landscape95160
2
gravatar for margherita.col
4 months ago by
margherita.col20 wrote:

Hi,

if you need to reconstruct the pedigrees, have you tried something like PRIMUS (https://primus.gs.washington.edu/primusweb/) ? You can input genetic data as well as IBD estimates.

Or you can figure out the relationship (if you need to simply identify parents) looking at the kinship value (> 0.5 twin/duplicate, > 0.2 PO or Full sib).

Hope this helps.

ADD COMMENTlink written 4 months ago by margherita.col20

This is definitely helpful. Thank you very much

ADD REPLYlink modified 4 months ago • written 4 months ago by landscape95160
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