Question: Project suggestions with paired Tumour and Normal RNA Seq data libraries
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gravatar for mandhirsikander
11 weeks ago by
mandhirsikander0 wrote:

I am a Bachelor's student and as part of my 3 month project I have to work around Paired Gastric Cancer Tumour and Normal RNA-Seq data libraries. I am looking for anys suggestions on what can I do as part of my project.

rna-seq • 126 views
ADD COMMENTlink modified 25 days ago by Biostar ♦♦ 20 • written 11 weeks ago by mandhirsikander0
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I think this is completely the wrong approach (please take this as constructive criticism and not as offence). As an unexperienced Bachelor student you will have to spend quite some on the technical details like using alignment and downstream analysis software. You should ask your supervisor for a well-defined and managable project that allows to be completed in time while niehter over- nor underdemanding you. Planning this is beyond your scope right now (at least it was for the guys I've met during my short career so far simply because you lack the experience and tend to underestimate the necessary effort.) I strongly recommend to sit with your supervisor and open-mindedly discuss the options.

ADD REPLYlink written 11 weeks ago by ATpoint18k

Thanks for the reply! I have been trying to work at MSI detection but I have hit rock bottom and not able to proceed hence it is a desperate approach I have been forced to try.

ADD REPLYlink written 11 weeks ago by mandhirsikander0

Is it not part of the project to search for RNA-seq applications ? I let you this link (which is just googled "applications RNA-seq"), pick one application and look for associated papers, then cross materials & methods to make your own pipeline fitting your data.

ADD REPLYlink written 11 weeks ago by Bastien Hervé4.3k
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