Gene-Patient mutation from Copy Number data

Question

[jctg]

Hi everyone,

I have some data about mutations. I am building a binary mutation matrix, where the rows are patients and columns are genes. I have created the matrix using SNV data. Now, I would like to use CNA data, in order to enrich my matrix. I have some segmentation data about CNAs. My question is: How can I 'transform' the segmentation file in data that shows the genes that were mutated in a specific patient? For example, from my segmentation file I would like some information like that:

Patient1: TP53, PTEN, NF1; Patient2: BRCA2, EGFR; Patient3: BRAF;

Thanks in advance

Regards

J