Question: How to find conserved regions from multiple sequence alignment
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gravatar for koushikayaluri
8 months ago by
koushikayaluri20 wrote:

I want to find conserved amino acid regions from multiple sequence alignment of different species. What is the best method to follow or tool to perform this mode of action?

ADD COMMENTlink written 8 months ago by koushikayaluri20

which program did you use to construct the MSA? and with 'conserved' do you mean exactly conserved in all sequences or might you allow some variation?

ADD REPLYlink written 8 months ago by lieven.sterck6.4k

Please show some effort/what you've tried so far.

This is a pretty basic question, so I can't believe you haven't found something to do this yourself.

What 'kind' of consensus are you looking for - your question is much too vague.

ADD REPLYlink written 8 months ago by Joe15k

A small hint. There are at least 5 posts in 'Biostars'

about conserved regions in alignment.

Go to the left hand upper corner of the page, press 'LATEST' button

and type 'alignment conserved regions' to the empty line in the middle

of the page. Look at the output (green blocks) and

right panel when you select your favorite block.

Another small hint - you will see a lot of useful posts at the

right panel of your own question in 'Biostars'.

If you are not satisfied, go to Google and type your own question there:

'tools to find conserved regions from multiple sequence alignment'.

In Google output you will see mentioned above 'Biostars' posts as well.

ADD REPLYlink modified 8 months ago • written 8 months ago by natasha.sernova3.7k
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