Question: Segmentation method in CNV
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gravatar for nesma.abdelaziz
14 months ago by
nesma.abdelaziz0 wrote:

I was searching for other methods of segmentation in Copy number variation and i was wondering if i can use swarm optimization as a method of segmentation to detect gain,loss in exomes.if this method can work?

sequencing cnv bioinformatics • 348 views
ADD COMMENTlink modified 14 months ago by ATpoint36k • written 14 months ago by nesma.abdelaziz0

Why 're-invent the wheel', i.e., do something that has already been done? The 'proven' methods are Hidden Markov Model - based methods, and Circular Binary Segmentation (CBS). You can use your time as you please, however, there are probably >100 CNV programs already in existence.

ADD REPLYlink modified 14 months ago • written 14 months ago by Kevin Blighe61k
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