Hi Biostars, I have two files containing the genomic ranges of all CpG islands and promoter sequences of Human genome hg19. I would like to do an association test between CpG islands and promoters. So I need to calculate the GC contents of the two files. However, I am not conversant working with genomic coordinates. Could somebody please help with a command that I can use to calculate the GC contents of the two files. Thanks.