I have gene expression data from two conditions having different sample sizes i.e 8 and 32. I want to build a correlation among all genes (for both conditions) for comparison. So, I used "psych" package from "R" which use t-test based statistics for p-adjusted values calculations.
Is this approach correct for the comparison of the networks (after taking significant p-adjust) between two experiments of different sample sizes?
or should I use another approach for p-adjusted calculations? If yes, what would you suggest?