How to use multiple control in Control-FREEC for CNV analysis?
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3.4 years ago
BioNoobie ▴ 20

We have 15 control sample and 30 test sample and want to check copy number variation in test samples. The sequencing method used is ion-torrent PGM,

A region in a chromosome is targeted and the whole region is sequenced including intron and intergenic region.

Which tool is best to identify CNV in the samples?

Control-FREEC is one of the methods we found useful but the control sample are not matched normal, can we use multiple control in FREEC?

targeted gene sequencing FREEC Control-FREEC cnv • 951 views

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