I am interested in a CDS at ENSEMBL, but I found it is Nontranslating CDS and not encoding for a protein. But for the same nucleotide sequence, putative protein is reported in NCBI based on computational annotation and translation. I would like to know, why in ENSEMBL it is enlisted as non translating CDS.
"putative protein" has very little meaning in the light of functional annotation, it's like 'hypothetical' , both are often the result of some automated pipeline. it even could very well be an over-prediction.
ENSEMBL uses the tag 'non-translating' CDS for instance to flag pseudogenes (== a gene like feature which likely are not functional as a proteins)