gene co-expression network
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22 months ago

Hi everyone,

  • Is it logical to analysis the gene co-expression network between samples with 3 repeats?

  • In order to construct a biosynthesis gene co-expression network which one is more valid? Meta-Analysis result or individual study result.

I would be very pleased if you could guide me.

RNA-Seq gene • 366 views
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Is it logical to analysis the gene co-expression network between samples with 3 repeats?

How many total samples do you have? - 3 replicates per group is fine, but how many total groups and samples do you have?

In order to construct a biosynthesis gene co-expression network which one is more valid? Meta-Analysis result or individual study result.

It seems that you have samples from multiple studies - it is correct? You should process these separately (construct a co-expression network for each study), and then do meta-analysis.

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Apologies for the delay in replying. There are two groups in this study, control (3replicates) and treated samples (3rep). there is just one group of treated samples.

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Your follow-up question is here: gene expression correlation analysis

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