Question: Looking for Yeast transcription factor - target gene matrix with weights (activations, correlations, ...)
gravatar for Andrei Kucharavy
11 months ago by
Andrei Kucharavy10 wrote:

I am currently looking for a matrix of transcription factors impact on genes in yeast.

For now, all the compendiums I am finding, only show binary data (presence/absence of a regulatory relationship), whereas for what I am doing I need continuous data - such as activation scores, percentage of explained variance by a transcription factor, correlations in expression, etc...

While there is an abundance of such databases for human and mice (eg TRRUST, CellNet, Network Compendium, ...) I have trouble finding anything for yeast, despite it being a significantly better explored and more easy to work with organism.

Where could I find such a database for yeast?

ADD COMMENTlink written 11 months ago by Andrei Kucharavy10

Have you looked at Jaspar and Yeastract?

ADD REPLYlink written 11 months ago by grant.hovhannisyan1.9k

Yes - Yeastract only have binary matrixes available for downloads, whereas Jaspar is more about transcription factors binding profiles than it is about regulatory interactions towards specific genes.

ADD REPLYlink written 11 months ago by Andrei Kucharavy10
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