Question: Looking for Yeast transcription factor - target gene matrix with weights (activations, correlations, ...)
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gravatar for Andrei Kucharavy
4 weeks ago by
Switzerland/Lausanne/EPFL
Andrei Kucharavy10 wrote:

I am currently looking for a matrix of transcription factors impact on genes in yeast.

For now, all the compendiums I am finding, only show binary data (presence/absence of a regulatory relationship), whereas for what I am doing I need continuous data - such as activation scores, percentage of explained variance by a transcription factor, correlations in expression, etc...

While there is an abundance of such databases for human and mice (eg TRRUST, CellNet, Network Compendium, ...) I have trouble finding anything for yeast, despite it being a significantly better explored and more easy to work with organism.

Where could I find such a database for yeast?

ADD COMMENTlink written 4 weeks ago by Andrei Kucharavy10

Have you looked at Jaspar and Yeastract?

ADD REPLYlink written 4 weeks ago by grant.hovhannisyan1.6k

Yes - Yeastract only have binary matrixes available for downloads, whereas Jaspar is more about transcription factors binding profiles than it is about regulatory interactions towards specific genes.

ADD REPLYlink written 4 weeks ago by Andrei Kucharavy10
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