I'm trying to align 319 variants of the rabies virus to see which regions are more highly conserved. However, all of the multiple sequence alignment tools I've found cap out at 20 sequences. Is there one I haven't considered/is there a way to string together a bunch of sequence alignments?
Question: Multiple Sequence Alignment for >20 Sequences
4 weeks ago by
griffinwhy • 0
griffinwhy • 0 wrote:
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8 days ago by
piet • 1.7k
piet • 1.7k wrote:
My preferred multi sequence aligner for the command line is mafft nowadays. The rabies virus has a genome size about 12000 nt. It should be feasible to align > 20 whole genomes with mafft on an standard PC, maybe within 10 minutes or less.
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