Question: Drug targets for hub genes
1
gravatar for banerjeeshayantan
7 months ago by
banerjeeshayantan150 wrote:

I have done differential expression analysis after which I have constructed the PPI network using the list of DEGs and then used Cytoscape to find the list of hub genes. Now how can I validate that these hub genes and the network that they form is indeed implicated in the disease I am studying. I also read that PPI network formed by hub genes can be used a prime drug targets. Is there any database that will take in the hub gene network and give us a list of drugs that might be used to target them?

rna-seq R • 250 views
ADD COMMENTlink written 7 months ago by banerjeeshayantan150

Have you tried Open Targets? With your hub genes individually.

ADD REPLYlink modified 7 months ago • written 7 months ago by genomax78k

thanks for the suggestion. I will look into that. Can you also please suggest some other methods to validate?

ADD REPLYlink written 7 months ago by banerjeeshayantan150
Please log in to add an answer.

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1313 users visited in the last hour