Question: How to amalgamate gene expressions grouped by UNIPROT?
gravatar for james
19 months ago by
james20 wrote:

I am helping prepare data downloaded from ArrayExpress to be used in a machine learning algorithm.

The algorithm expects one sequence of gene expression values for each UNIPROT. However, the data is organized (as usual I assume, but I am new to this area) so that there is one sequence of gene expressions for each Probe ID.

I did a look up that associates the Probe IDs with UNIPROTs, but it is a many-many relation. So each UNIPROT has multiple associated Probe IDs.

Is there some "standard" or "proper" way to combine the gene expression values for each UNIPROT? Of course, I could take the mean or median gene expression value over all Probe IDs associated with each UNIPROT, but is there a better way?

sequencing • 278 views
ADD COMMENTlink modified 18 months ago by Biostar ♦♦ 20 • written 19 months ago by james20
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