Is it possible to introduce mutations (SNV/Indels) in precomputed lastz alignments
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2.1 years ago
Saad Khan ▴ 400

Hi,

I have multiple resequencing files from multiple species that I am trying to compare. For each individual vcf file I generate a alternate fasta using FastaAlternateReferenceMaker. I was wondering if there is a tool/package that can introduce the mutations (indel/snv) in the precomputed alignment last files without having to re do the lastz alignments for multiple alternate fasta files.

Thanks!

FastaAlternateReferenceMaker lastz pairwise_align • 550 views
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