Tool:Single (i) Cell R package (iCellR); a CRAN R package for single cell data analysis (i.e scRNA-seq, scVDJ-seq and CITE-seq)
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Single (i) Cell R package (iCellR) is a toolkit that allows scientists to work with data from single cell sequencing technologies such as scRNA-seq, scVDJ-seq and CITE-Seq. Single (i) Cell R package ('iCellR') provides unprecedented flexibility at every step of the analysis pipeline, including normalization, clustering, dimensionality reduction, imputation, visualization, and so on. Users can design both unsupervised and supervised models to best suit their research. In addition, the toolkit provides 2D and 3D interactive visualizations, differential expression analysis, filters based on cells, genes and clusters, data merging, normalizing for dropouts, data imputation methods, correcting for batch differences, pathway analysis, tools to find marker genes for clusters and conditions, predict cell types and pseudotime analysis.

CRAN : https://cran.r-project.org/package=iCellR

GitHub: https://github.com/rezakj/iCellR

Link to a video tutorial for CITE-Seq and scRNA-Seq analysis: https://vimeo.com/337822487

scVDJ-Seq CITE-Seq scRNA • 1.9k views
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