Are probes flagged as cross-reactive on Illumina's Methylation 450K still flagged on the EPIC methylation array?
1
2
Entering edit mode
2.6 years ago
dodausp ▴ 160

Hi there!

My question is pretty straightforward: are those probes described on Chen et al., 2012 paper for Illumina's 450K methylation array still valid for the EPIC version? If not, would there be an updated list of probes? Or would you skip that filtering step from your pipeline when performing EPIC array analysis?

Thanks in advance!

illumina microarrays methylation • 1.2k views
ADD COMMENT
2
Entering edit mode
5 months ago
Basti ▴ 330

Hi, I personally use the dropXreactiveLoci function from the maxprobes package in my pipeline. As you can see on their GitHub page, they collected cross-reactive identified probes on both EPIC and 450k from 4 studies : https://github.com/markgene/maxprobes

ADD COMMENT

Login before adding your answer.

Traffic: 863 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6