Question: How to detect survival groups?
0
gravatar for MatthewP
16 months ago by
MatthewP880
China
MatthewP880 wrote:

Hello, given TCGA data how can I separate patients into 2(high, low) or more groups with statistics method?
This paper has mention Interval Coded Score index(ICS) and Rpart
I want to know what methods usually used to detect survival risk group? And want some ready-to-use tools recommend. I already found RPART TOOL, but not ICS. Thanks.

survival tcga • 315 views
ADD COMMENTlink modified 16 months ago by Kevin Blighe71k • written 16 months ago by MatthewP880

Or maybe I just sort the survival data by time(died and censored together) then devide by median?

ADD REPLYlink written 16 months ago by MatthewP880
0
gravatar for Kevin Blighe
16 months ago by
Kevin Blighe71k
Republic of Ireland
Kevin Blighe71k wrote:

Any method is used to divide the cohort into strata for high|mid|low, et cetera. That is, there is no standard that is used, and neither should there be due to the fact that this is exploratory type work.

You can try:

  • quartiles
  • tertiles
  • binary classification (based on median or something else)
  • Upper 10%, mid 80%, and lower 10% of the range, et cetera
  • Z-score cut-offs

Kevin

ADD COMMENTlink written 16 months ago by Kevin Blighe71k

My concern is treating died and censored data as the same if I split survival time simplified.

ADD REPLYlink written 16 months ago by MatthewP880
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