Correct data for methylation data plotting (circos plot)

Closed:Correct data for methylation data plotting (circos plot)

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4.5 years ago

maria2019 ▴ 250

I have a basic question on the NUMBERS (data) that should be used to plot hypo- and hyper methylation circos plots.

I want to plot a simple circos plot like this paper (DOI=10.3389/fgene.2019.00184): enter image description here

The blue circular bar plot represents percent of hypermethylation and the red circular bar plot shows percent of hypomethylation per region (Q-value <0.01 and **methylation difference >25%**). DM regions in this figure are mean DM per 10 Mbp window.

My data looks like this:

enter image description here

Should I just plot 70.9 as hypo methylation and 45.7 as hyper? is that it?

Also, what would "methylation difference >25%" mean? does it mean 70.9/86.2 should be larger than 25% in order to be included in the circos plot?

methylation circos plot • 285 views

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