Regarding WGCNA gene expression data
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2.1 years ago

Currently I am working on WGCNA, using gene expression data. In WGCNA correlation and p-value is default or we can reset it. I am confused. if i want to reset the correlation & p-value then how to reset it? Plz help me out.

genomic • 532 views
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Hi, What do you mean correlation? Do you mean correlation gene expression profiles with clinical traits?

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I have a matrix of RNA-seq data of genes vs samples. I want to find out co-related genes from WGCNA. I am not using any clinical trait.

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ok. you mean that you would like to change correlation method. in adjacency() function you can change the type of correlation method. default is the Pearson correlation coefficient.

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No I dont want to change the method of correlation.I want to change the correlation value for gene expression prediction like if I will get 0.7 then we can say that it is good result. one more thing how can I edit the p-value in code.like someone taken 0.05 and others are taking 0.01.

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If you want help, please show all of your analysis steps and also paste a sample of your data here. Unfortunately, textual descriptions are often unhelpful.

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