Question: How to extract hypervariable region of mitochondrial dna from its fasta file?
gravatar for iamakhilverma
8 months ago by
iamakhilverma0 wrote:

Recently I've done some analysis on mitochondrial DNA and now I want to run the same analysis on only hypervariable regions of mitochondrial DNA to see whether the changes that I have observed are linked to only hypervariable regions or not. To do that, I'll need to make new fasta files from the mitochondrial DNA entries that I have and I want to know how to extract those. Any leads will be appreciated.

sequence gene genome • 233 views
ADD COMMENTlink written 8 months ago by iamakhilverma0

There are several hypervariable regions in mtDNA, I know about at least two of them.

There is a kit to extract them

See this article, it may help you.

mtDNA Variation and Analysis Using MITOMAP and MITOMASTER

Marie T. Lott, Jeremy N. Leipzig, Olga Derbeneva, H. Michael Xie et al.

Also see the post below, and you may try to determine it by yourself.

A: Heteroplasmy detection program

ADD REPLYlink modified 8 months ago • written 8 months ago by natasha.sernova3.7k
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