I'm doing some research in WGBS and want to distinguish differential methylated CpG island from tumor and normal (10 samples for each group). I tried DMRfinder, but it combine CpGs to form regions, seems do not support customized regions.
I can just compute methylation level for every CpG island(download from UCSC) and do t-test, but I want try several tools to comfirm the results.
Is there any tools/packages to infer differential methylated island from overall CpG islands?
Thanks for your help!