Annotation of structural variant mechanism
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4.4 years ago
IP ▴ 760

Hi biostars,

I have detected a set of deletions in my samples, and now I want to classify the deletions into a DNA repair pathway such as Non Homologous End Joining or Homologous Recombination. I have seen that there are some tools out there (e.g. BreakSeq2) but I have not found any evaluation or review of the tools. Hence:

  1. Has somebody use a tool for annotating the Structural variant mechanism into a DNA repair pathway?
  2. If so, Which one would you recommend?

Thanks for your help!

sequencing structural-variation annotation • 577 views
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