fastqc per base sequence content and kmer content fail

Question

[houdn923]

I do the fastqc with my fastq data, and "Per base sequence content" and "kmer content" are fail, but others are pass, so should I do something for these data? Or which software can I use to deal with them? I just want use them to do the Monocle.

[ATpoint]

Should I remove Kmers identified in FastQC?

Ngs-Qc-Per Base Sequence Content Failed